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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '529f3dee2f83386b4d67aeffd5fbc0452abe7b47db9ef2d978c54cd5fc25a101' 
  AND token = 'i4//2WJU7UVOq5M+FoxBWRXVSdMAgDnuxCw8F7PCn60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}