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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e87c9c5fc165757f5e59c05cd3472247d8adaafc32f61fe30072e84e9758506' 
  AND token = 'a8G+ee+MtKhsdzP7e6/7vevquZZsQEzCbCNIQc5/gyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}