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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258fda93ee2f5277cbcde5cf76a99e7adb29fb8a010aef15a8884035e4c4918b' 
  AND token = 'NmfLQk9W/HllvRqqjToMprq+pGbC77vR9N3eJt1qScM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}