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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4559bcd9e32f2aae812678d29d0683111099071671079638a54559aa80f457e7' 
  AND token = 'vlLzPfd6G9c7qRB8TwvArUWpGY1WIXcmyMdzqhYNv50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}