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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ab65a0070f1a0f7e7098017090f28d5f8f26b7f33af396ceff4bc2aa9631c0c' 
  AND token = 'g3EfnumC8OGZqvWSTKj+jujPWmN92D+Z90EzZYKeqBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}