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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c2edc3e2af3837e6e1a7fc8977c0f8bda75bc23d26b783414123f25b54f8c8c' 
  AND token = 'WOsD/rh6n80KbnHJ8jJMeuYw+uyHdNtmb10bXEQOiGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}