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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df1f7eadfcb5abf9b42f43c518bb54b34230cdb1aa80c0f70b07e4899639c813' 
  AND token = 'DZ6ZbkvJd21Y60FbdLAMmHUwx1W5MpTfHr/vQ8uyhFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}