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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddc48d7dd3700d3abcf6b8813cf63395af07a268807550ed0789b79aa9c7586a' 
  AND token = '4Y2kMvP+2mE2gfhkAhmqCE8qXfdQXJau+AKXB4fCuqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}