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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8331af466ee9b86a7e2ac36961ffdd4eabd94ed2719f0ff12060ef977f5a32c' 
  AND token = 'etlj3mJ2KS3BmUS38rZTPKnIPlAiY+FQNa1z6bk6Ifk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}