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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03d880eb626b497121061a1728176a854cd1b897adb3d834df891e7a2e28d7b8' 
  AND token = '8c2vnrbHX33DI6zILA/YCXilolHduBwYY2/iqMWnigY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}