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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42dfc300c8b0f403fd063e033fa938ca7c6fbdc2539b42f7e343038f5e1f3ea5' 
  AND token = 'vCaRtnAr1WxgCcJCfvE4sqWx5E7GUPuqynlZusQU1lQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}