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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10ceae42d814b782eb8b4a286c20d95343b44dc8587d907e7826d02043110ac3' 
  AND token = '+k/KPpL2VDpkXHb53X28o0clR8sJW5yiwhAiA94iURk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}