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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd95f3439bee482ef050ce936095a8291d4ff696a39eb8e36a4859cb47de04316' 
  AND token = 'zNZ1z0DsUnev+v0yTMvg7uNVmulH/6eszpV9k8pbnZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}