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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57185e1aab4fb4e49f7bf842d29419fb6ea8365c51307106f0e73ad69b131c59' 
  AND token = 'kO9iM10DKHlaTuTCZ3R8sgnzzgSOy4pmnzMu3Y01GGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}