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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f7e166f5dd93390108f23b80b77a8fc4930397a153645e70019ec265da00d59' 
  AND token = 'XX00NIIv+LSsk76CgDJ3r0XtLkffWQK+vCiNV8+J1ZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}