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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00d123c4d347732dedaeed17e1110db1d91ee2ec7c7b26da7ad8f50beeb3a442' 
  AND token = 'Oy9dE3+vAEGGBGqe4kkjFPEFxvTnOAx7DtjtGPu0kgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}