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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dee4ffc9628c7d08281690e1e646ec4847769f52e3de3df5c5047c69db3a121a' 
  AND token = '0L2922hMWCW8ZIcOOyG269e1oRdFlqRJLnyiIgjhRN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}