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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2ddea127ba1dda9c9e13663aadad3378d740920a8a81e45fd2a9a9862b156f' 
  AND token = 'J4aI8aGwMO5tQoruaG5q5nVTuYGQ3WSYEQmPxwQ5yKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}