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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22342f3653658df2f7fc14dc9051937b264ab3193d3135eb17d6f0f010a0bca3' 
  AND token = 'J6mZ1XkH3iJXUXz3yLJ4lALhzaJ2Cthb3VojboklHDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}