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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d436394656a35991b763e79a59758367c65bfcd23c99d9a56cb8f53023ed32f' 
  AND token = 'jnWiyv8nmCja6rpRkYIiSuWXPtU+ZgKq9Ksa0lb1Wus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}