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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cec81bcccdc978f0de94137d7e971a3dd70d2719031ad6dfe0f68a222e8fc23' 
  AND token = 'licB1BEfKa2xNe0BPuMSDpH/FHI1kQ1+NHPpfcyuBjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}