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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '379f24f618b32d908759f9d4c0fcfdd7c4bb0ed60113c78fa1bcc8329424b394' 
  AND token = 'cE/lc/SDX7u1kiqev70TDm4Wk3rxT8abrLfyYt3Jsbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}