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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8645db2bd036f8a557131d965b16338dd6b97cd29d567fd28fafdac4039454a5' 
  AND token = 'U7lv5u19sRpZoXKYtqk77qKO/e5riwMPKif8saw7wJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}