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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f8102cfb0f0f47f3f1712186bc9cf533727cc9200afa59d4cede430a768d46' 
  AND token = 'CP343ziqTvqacpg5xbuZH32d3uGjZg6H18+QxV7v6fA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}