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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f3f454cfc6f7c38eb250782431e426c6290df1010af287b07535f245832a680' 
  AND token = 'B2XMdUwP3EUP3OmHf7LQ2njqv9S8DFtwRaYpTulXwEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}