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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d66525428030daeed8a9c967592f70a457a365efab5c90ab5a0a0dc08a08c37' 
  AND token = 'O3On2B4vaWXZeju+uPRN6WhsenxRCoVxQv2nF+9gdH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}