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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b5f10cdcd2f3520c516659cee410e2629e2edf73dec0d186b6bffd7f89f0b00' 
  AND token = 'bHbFXYmVGkLbSbo/aTl2VhmNVfI0HhXi95W7J15BiXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}