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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f80332d64618ca7d105996843381aa0986ed953f2d3a348abd4dfc6677b1c0a4' 
  AND token = '3UmGpKROHt4KZp/2NzDQr008txsV9GrL7+ez1EfIiUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}