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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea09a6052dfc5e0f12700207b909a19165c555dd1973cd472e5978349c493cde' 
  AND token = 'BrF0x2dQnKaukWX+P5ySr7KugSSZUuflVeFSVCVWivo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}