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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53342653860a197149ffa8f9d6d036ebc921721924e16fe602f5a2519097072' 
  AND token = '/7zxldoorszuYRYMFZj1w5bxnEeXmrh0Z7tM9dKt3AA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}