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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78503be7d291a2828bdfa7e447a360739ce81bc902a692c06f0a5fbb653aede6' 
  AND token = 'eA12dRY+Y4SD8k784DugefB+hgIS1WdUcXkxOCF1WoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}