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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a123a2b23d4283dad02d68d987f9c7b4e5dcca225e52701f5b4bdd20076e77c9' 
  AND token = 'FYUdvxbGL6dzQ3ZPp+SBiKlY7LRa1/i6r+fsrbq03QY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}