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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf0d87044e34943afd1d9e9a509db924b973e1818dde88aa5e1878f2eaa9b2f1' 
  AND token = 'IlmS4D8TGNpKnCqFzEyE+F30jOl5gjnUIPlRe3GXA3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}