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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c664d93d6252aa992efc36ba65cc39181fb60f09c9adefc0d8d8be5e2d189ed' 
  AND token = 'dOQ0si7wxKdqOd2I9ZUXg6Sxbw2gc6ww1GOkaGIHRPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}