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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae42dcdc6c7ba577057ce0237021f26afad6d9ae321c13bb05d5c51222431cb' 
  AND token = 'kJ2qQq+UcZXJO2QXk46S/ZyzlAEVebebThiTHpvN0eE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}