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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3339f4488aa12059d40f5fc5d1c7df54baf3e4f06d3e76d588a8da1d7024123d' 
  AND token = '3SPULy/1VUJgFfuegm+lY0deC4W1Q6aQ3U5oVBEeV0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}