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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c214309d909952a89a4e98b9e0fa23206590fddd3166dca3f91734cdcec2c8' 
  AND token = 'CfpyNG4WL0NuMCnWpn+rIA9WNi57L1i2QTcFu/2+EcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}