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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12fd11c7db7e25b9bb81b623b9e26f9674a7b1b63035e76d9b38bcde16b3014c' 
  AND token = 'LmPToQMy4jbgKL9WKItt6G32jVOBdVpbCp5lcp1xbwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}