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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a754b6c8424bc7503dc6d15879b07e301a3d3fa8b012e2d00fa9722cb10f959' 
  AND token = 'xVwoDPeMUSu73MKXYMZSIDoJUw8lEpekdSA+s6p7ETc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}