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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a69ff4d17b81a9848a87119af00eb38a7625d0d3823aadaa880712698f039f' 
  AND token = '2jjUkmPIYM0hPQKCyyZGp83mKEcUDpsAgMi8f9QU3i8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}