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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52f8b9f5afe8e3239c04abeb9291cca3f8b0af035344ed0f73b7d8079c230da1' 
  AND token = 'IILJC6nwqBJq55Mwzk8E+IZ8LgLSfZnYXZPLdYeeIxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}