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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b213aab3c436b85f704b9f2c0ea7a4bfe5ca5c0a2f38ac6ab7efe7516a30520' 
  AND token = '8dO1fisvPX+CID2dtnAP/IfziizAd8pxeY2XiUFgPc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}