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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd05c514634504bcc61823c9037be00f4af07cefb01957cf32a6d8906d21a2c8' 
  AND token = 'V+LNItmHalrYAZjlZ70TOn000lE7qKiylA788/5h2hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}