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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5d16d75ed65f36742eb1eae264215e1281c623a7daca7ea7964626cefa97a24' 
  AND token = '8N3QEBToeQLh/63wU+mhd4oYbmAg2hldw07JgGnklj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}