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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '244f3bc5939c1fc7752db2264b568edeb9d57e2fdc60efa43964814c1e8858ce' 
  AND token = '0y2/MnltTT8G0XSSWTyI1ndeRhQTlXnd8TQLlXgEd5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}