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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ae2024374f07bc62a6075e02c81112c3abe3b18d9a526a399d7cbed98de87e4' 
  AND token = '+rYsKAXbjXGc7O9mD4skyHiBuInTarUOArDHTe0ZX4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}