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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1155a00f536beb478c887295f65bab24b2280df2727597821645f37111d41244' 
  AND token = 'bHFJ8/Pqi1/9s19AyYasoTGJl3GeVeMw0r5lCNRzMEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}