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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b3b568b97badf03a2c430acce9afff81cfcd1db105cb33436cc709a9e69f17' 
  AND token = 'CTTzdcLDPKdyRaBhEWzv4JfQlT62X3uT5EDd6B9d8uA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}