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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45dca64f1aa0cadf33f92a970886bf9c2c5a75d2540de9820aec95678413fba2' 
  AND token = 'P5RQkyDur0C6GcOEvfvye2/LN7ksFVIz6FrqvUS2wRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}