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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4c896a6e886da6d24752b70409dd294237221e48a6ab1add395ea7b9e3ed12' 
  AND token = 'xizG8x1yyyHDZhmkRcnz6UXGDSJkGpDaa1+3PwVjo8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}